The mission of CABBI is to meet a major challenge facing the world: how to provide sustainable sources of energy for societal needs as the population continues to grow and global change accelerates. CABBI will develop efficient ways to grow, transform, and market biofuels and other bioproducts. The vision of CABBI is to integrate recent advances in genomics, synthetic biology, and computational biology to increase the efficiency, sustainability and value of biomass crops. This holistic approach will help reduce our nation’s dependence on fossil fuels thereby increasing sustainability and national security.
CABBI is founded on the “plants-as-factories” paradigm, in which biofuels, bioproducts, high-value molecules, and foundation molecules for conversion are synthesized directly in plant stems. CABBI will focus on sorghum, energycane, and Miscanthus, which are high-yielding throughout the rain-fed eastern U.S.
Foundation molecules produced in plants will be efficiently converted using the design-build-test-learn framework to diverse, high-value molecules such as biodiesel, organic acids, jet fuels, lubricants, and alcohols using technologies developed in a versatile, automated biofoundry for rapidly engineering microbial strains.
The Center will employ a data-driven integrated modeling framework to predict which feedstock combinations, regions and land types, market conditions, and bioproducts can support the ecologically and economically sustainable displacement of fossil fuels. The result will be an overarching framework for viewing the research through an environmental and economic lens.
CABBI, a U.S. Department of Energy Bioenergy Research Center, is supported by DOE, Office of Science, Office of Biological and Environmental Research.