As a daily utensil and artefact used since the Last Glacial Maximum (Wu et al., 2012), ceramic is direct evidence of human activities. A large number of ceramics in numerous sites were found on the Qinghai-Tibetan Plateau (QTP). The ages of most ceramics were determined according to the conventional method such as culture characteristics and radiocarbon dating on the charcoal or bones from the same cultural layer, but lack of the luminescence studies from the ceramics. In this study, five sand tempered grey ceramics in Talitaliha site in Qaidam Basin were selected to do the OSL dating based on quartz and K-feldspar. The reliability of the OSL dating is verified with 6 independent radiocarbon age including 3 charcoal and 3 bones from the same cultural layer. The result shows that luminescence ages on ceramics have good agreement with the 14C dating results. It suggests that OSL dating on ceramics has great potentials in archaeological investigation on QTP. The age of Talitaliha site is between 3400-2800 Cal yr BP. Combined with previous studies, Nuomuhong (NMH) culture existed during 3400-2450 Cal yr BP, suggesting that the prehistoric human permanently occupied this hyper-arid region since that time.