60 / 2023-08-15 14:12:35

Facile Synthesis of Phosphole Derivatives via Phospholyl Lithium Synthesized Directly from White Phosphorus

P4 Functionalization,Organophosphorous Compounds,Dilithium Reagents

Phosphorus in Synthetic Chemistry > 1) Phosphorus compounds as catalysts

    The development of new strategies for direct activation of P₄ is rapid these years, and one representative method is the activation of P₄ by dilithium reagent.^[1][2] To apply these strategies to the synthesis of high-value organophosphorous compounds (OPCs) has practical significance and application value, such as to synthesize bisphosphine ligands. Here, taking advantage of the newly developed strategy with dilithium reagent, facile synthetic routes of diverse phosphole derivatives from white phosphorus were developed with phospholyl lithium as the synthons (Fig. 1).