205 / 2024-07-13 13:46:02

Transforming Speckles: Shaping and Learning in Deep-Tissue Optics

Optical speckles,deep tissue,wavefront shaping,deep learning,multimode fiber

The application of light has significantly expanded the scope of biomedicine, encompassing imaging, sensing, treatment, and manipulation. However, the high-resolution capabilities of optical techniques are often restricted to shallow depths or thin samples due to the strong scattering nature of light in biological tissues. Scattering is a prevalent optical phenomenon where light reflects and scatters within non-specular surfaces or propagates through media like turbid liquids and biological tissues, accumulating optical phase and wavefront distortions. These distortions result in seemingly random visual speckles, which can hinder information recognition and interpretation. Overcoming or mitigating these effects is crucial in many applications. This talk will discuss recent efforts and advancements in several dimensions—physical modeling, optical wavefront shaping, and deep learning—to achieve high-fidelity and robust information extraction and image reconstruction from optical speckles. Additionally, it will introduce an innovative strategy using scattered light as a carrier for ultra-long key information optical encryption and optical logic operations. The talk will also acknowledge existing limitations and outline potential future development paths. These emerging technologies hold promise for advancing optical imaging paradigms.