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Optimal Regimens and Clinical Breakpoint of Avilamycin Against Clostridium perfringens in Swine Based on PK-PD Study

Clostridium perfringens causes significant morbidity and mortality in swine worldwide. Avilamycin has shown good activity for treating C. perfringens and demonstrates no cross-resistance. This study aimed to formulate optimal avilamycin treatment regimens for C. perfringens infections based on the clinical breakpoint (CBP). This study aims to establish optimal avilamycin regimens for C. perfringens infections by determining the CBP, which has been based on the COWT, COPD, and COCL of avilamycin against
C. perfringens.