70 / 2024-10-25 03:52:44

Antibiotic Stewardship in Dairy Farming: A One Health Approach Using Phenotypic and Genotypic Surveillance

Antibiotic misuse in dairy farming plays a critical role in the development of antimicrobial resistance (AMR), posing risks to human, animal, and environmental health. This ongoing study adopts a One Health approach to investigate AMR patterns and their relationship with antimicrobial use (AMU) in dairy farms in Chattogram. Samples are being collected from 50 farms, including bulk milk, milker's hand swabs, and environmental samples. The project will utilize microbial culture, MALDI-TOF MS, and antimicrobial susceptibility testing to identify bacterial species and assess their resistance profiles. Concurrently, AMU data is being collected to explore correlations with AMR, while whole genome sequencing (WGS) and phylogenetic analysis will be used to study the transmission dynamics of resistant bacteria. The outcomes of this research aim to inform targeted antibiotic therapy, improve farm biosecurity practices, and ensure adherence to withdrawal periods, ultimately contributing to therapeutic success, economic efficiency, and farm profitability. By integrating AMU and AMR data, this research seeks to provide actionable insights to mitigate AMR in dairy farming, safeguarding both health and sustainability.