Non-Deterministic Approaches are technologies aimed at understanding and managing the variations and uncertainties that are inherent in the design, production, and operation of physical systems to quantify the reliability and performance of these systems and enable confident decision-making. The NDA conference is a forum to discuss both the development of new methods for solving these problems and the application of non-deterministic approaches to problems of interest to the aerospace community.·Uncertainty quantification and management·Optimization under uncertainty methods·Model calibration, verification, and/or validation·Reliability analysis methods and applications·Validation and uncertainty quantification of ICME models·Special Session: Uncertainty Quantification and Management for the Digital Thread and Twin·Special Session: Validation & Application – ICME for Structural Analysis·Special Session: Sandia End-to-End UQ Test Problem·Special Session: A Framework for Managing Multiple Information Sources of Multi-Physics Systems·Special Session: DARPA Efficient Quantification of Uncertainty in Physical Systems (EQUiPS) Program