We warmly welcome all the distinguished guests to the Second International Conference of Microfluidics, Nanofluidics and Lab-on-a-Chip in Beijing from June 8-10, 2018. This conference is sponsored by Beijing International Center for Theoretical and Applied Mechanics, Institute of Mechanics of Chinese Academy of Sciences and Beijing University of Technology.Research on Microfluidics, Nanofluidics and Lab on a chip has advanced rapidly over the past two decades, which is a cutting-edge subject and has great application potential in biochemistry, human health, new energy, advanced materials, and so forth. It has produced direct and significant impact on various fields in science and engineering. This conference is intended to provide a highly interactive forum to bring together researchers, engineers around the world with the aim of exchanging the knowledge of the state-of-art research and development in this field, and to inspire new efforts to advance the frontier of the research.This conference will have 8 plenary speeches, 40 keynote and invited talks and more than 300 oral presentations. The authors and attendees are from more than 20 countries and regions. As the conference chairs, we would like to express our deepest gratitude to all the committee members, track and session chairs, local organization committee chair and co-chairs, and student assistants, who have contributed greatly to the success of this conference — it would not have been possible without your time, energy and effort. We would also like to send our great appreciation to all plenary speakers and all of the contributors, whose high-quality work, careful analysis, and tremendous insight have helped to make this conference a successful and memorable event.