The 22nd Symposium on Chemistry and Science Education taking place at the University of Bremen in June 2014 continues a long tradition of symposia stretching back to 1981. In 2014, the symposium will coincide the end of the United Nations worldwide Decade of Education for Sustainable Development (DESD) spanning from 2005-2014. Already in the past, the Dortmund-Bremen-symposia on science education focused the question of how science education research can help to improve chemistry and science teaching and learning, and also which are the objectives to be followed. In recent years, debate on the challenge of the sustainable development of our future added another dimension towards this discussion. This additional focus and the coincidence with the end of the DESD provoked the organizers of the symposium to entitle the 2014 symposium: “Science Education Research and Education for Sustainable Development (ESD)”. This title simultaneously maintains and further develops many topics of the past symposia from 2002-2012, in which we discussed the orientations and directions of science education research, questions of contemporary and successful science learning, and the role of research on science teacher education for it. The symposium in June 2014 will reveal and evaluate all these aspects even more in connection to a goals and strategies focusing Education for Sustainable Development within science education.