The 2nd International Conference on Image and Signal Processing (CISP 2009) and the 2nd International Conference on BioMedical Engineering and Informatics (BMEI 2009) will be jointly held in Tianjin, China. Tianjin is one of the four municipalities in China. It is a financial and commercial center in North China, which is known for its numerous travel resources and rich history, such as Gu Wenhua Jie, Dagu Emplacement, Huangyaguan Great Wall, Dule Temple, Haihe River, Panshan Mountain and Food Street. Tianjin Binhai New Area lies in the center of the Circum-Bohai Region and the eastern seaboard of Tianjin. It is located in the juncture of the Beijing-Tianjin City Belt and the Circum-Bohai City Belt. It is the gateway to North China, Northeast China, and Northwest China. Lying in the center of Northeast Asia, it is the nearest point of departure of the Eurasian Continental Bridge. CISP’09-BMEI’09 aims to provide an high-level international forum for scientists and researchers to present the state of the art of multimedia, signal processing, biomedical engineering, and biomedical informatics. The previous CISP’08-BMEI’08 attracted over 2600 submissions from more than 30 countries. All papers published in the proceedings will be indexed by the EI Compendex and ISTP.