CELL AND TUMOUR BIOLOGY

• Cell Proliferation/cell cycle

• Cell Death / Autophagy

• Oncogenes and Tumour Suppressor Genes

• Tumour Progression: Invasion and Metastasis

• Metastases and EMT

• Tumour Microenvironment

• Tumour Angiogenesis

• Tumour Immunology AND Inflammation

• Aging and Cancer

• Senescence

• Cancer Cell Metabolism

• Cancer Initiating Cells / Cancer Stem Cells

• Tumour heterogeneity

CANCER GENOMICS, EPIGENETICS and GENOMIC INSTABILITY

• Genomic Alterations in Cancer

• Functional  Genomics

• Epigenetic mechanisms and RNA

• Genetic instability

• Deep sequencing

SIGNALING PATHWAYS

• Receptors and Signal Transduction

• Gene Expression, Transcriptional Regulation

• Systems biology

• Computational models of biological systems

• Omics technologies

CARCINOGENESIS

• Mutagenesis, Carcinogen Metabolism

• Promotion and Progression

• DNA Damage and Repair

• Viral Oncogenesis

TRANSLATIONAL RESEARCH

• Organ Site-Specific Investigations: Preclinical, Diagnosis, Treatment

• Molecular pathology

• Biomarkers with clinical relevance, imaging

• Prognostic biomarkers of therapy response

• Prognostic value of oncogenomics

• Clinical Phase I/II trials with targeted drugs and novel agents

• Bioinformatics in therapies and clinical trials

• Animal models of cancer

• Infrastructures (biobanks, databases, genomic resources, others)

EXPERIMENTAL / MOLECULAR THERAPEUTICS, PHARMACOGENOMICS

• Drug Discovery / Drug Design

• Novel Targets, Delivery Systems

• Mechanisms of Drug Action, Drug Profiling

• Drug Resistance

• Novel Approaches to Diagnosis of Cancer

• New Therapies

• Companion diagnostics

• Personalized medicine

TUMOUR IMMUNOLOGY

• Tumour Immunology

• Immune Suppression and Escape

• Tumor antigens and immune effectors

• Immunotherapy and Cancer Vaccines

• Cancer vaccines: preclinical and clinical studies

RADIOBIOLOGY / RADIATION ONCOLOGY

• Tumour Cell Sensitization to Radiotherapy

• Radiation-activated Signaling Pathways

• Cell Cycle and Apoptosis in Radiation  Responses

• Radiation Oncology; Preclinical and Clinical

• Translational radiation research

MOLECULAR AND GENETIC EPIDEMIOLOGY

• Risk Factors

• Biomarkers

• Risk Assessment

• Susceptibility Genes

• Genotype / Phenotype Correlations

• Genetic Polymorphisms and Cancer Susceptibility

• Epidemiology 

PREVENTION and EARLY DETECTION

• Preclinical Prevention Studies, Markers and Prevention

• Clinical Prevention Studies

• Vaccination Against Cancer

MOUSE MODELS

• Transgenic models

• Chemical carcinogenesis

• PDXs

• Humanised mouse models

OTHER