This workshop explores novel concepts to allow for flexibly centralised radio access networks using cloud-processing based on open IT platforms, in coordination with network functions virtualization technologies and MEC (Multi-Access Edge Computing), that are recognized as key enablers for the definition of future 5G systems. The aim is to allow for a guaranteed high quality of experience for mobile access to cloud-processing resources and services, and to allow a future network evolution focused on energy efficiency and cost-effectiveness. In fact, all future innovative network solutions will be conceived and deployed with a long term perspective of sustainability, both in terms of energy consumption of mobile network (and related interoperability with terminals) and cost efficiency of the different deployment and management options. This requires new concepts for the design, operation, and optimization of radio access networks, backhaul networks, operation and management algorithms, and architectural elements, tightly integrating mobile networks and cloud-processing. This workshop will cover technologies across PHY, MAC, and network layers, technologies which translate the cloud-paradigm to the radio access and backhaul network, and will analyse the network evolution from the energy efficiency perspective. It will study the requirements, constraints, and implications for mobile communication networks, and also potential relationship with the offered service, both from the academic and the industrial point of view.